Interim results for the six months ended 30 June 2018

Destiny Pharma plc

(“Destiny Pharma” or the “Company”)

 

Interim results for the six months ended 30 June 2018

 

Clinical progress and pipeline expansion in dermal infections; well-funded through to H2 2020

 

Brighton, United Kingdom – 26 September 2018 – Destiny Pharma (AIM: DEST), a clinical stage biotechnology company focused on the development of novel anti-microbial drugs, which address the global problem of anti-microbial resistance (AMR), announces its unaudited financial results for the half-year ended 30 June 2018 and additional updates for the year to date.

 

Financial highlights

  • Strong cash position with cash and term deposits at 30 June 2018 of £15.1 million (30 June 2017: £0.9 million; 31 December 2017: £16.7 million)
  • Expenditure on R&D in the period of £1.3 million (half-year 2017: £0.3 million; full year 2017: £0.8 million), reflecting the increased investment in clinical programmes as described below
  • Company well-funded through to H2 2020

 

Operational highlights

 

Clinical – prevention of post-surgical infections

  • US Investigational New Drug (IND) application opened for XF-73
  • US Food and Drug Administration (FDA) Fast Track designation granted for XF-73
  • Clarification, through dialogue with the FDA, of the Phase 1 and Phase 2b clinical trials programme
    • Phase 1 dermal safety study for XF-73 in abraded skin completed successfully in July 2018
    • Phase 1 dermal safety study of XF-73 nasal gel starting in October 2018
    • Phase 2b nasal programme remains on plan to report in H2 2019
  • New, independent market analysis, commissioned by the Company and completed in May, supports clinical need in US for XF- 73 target product profile and confirms $1 billion peak sales opportunity

 

Clinical – treatment of dermal infections associated with DFUs and burns

  • Identified two further indications with unmet need which new formulation of XF-73 could address:
    • Infections associated with diabetic foot ulcers (DFU) and burns wounds
    • Destiny estimates this is a $500m global peak sales opportunity
    • Completed Phase 1 safety study in abraded skin supports dermal potential
  • New programme for XF-73 dermal infection treatment announced today planned to deliver Phase 2 ready package by H2 2020

 

Pre-clinical / research programmes

  • Research collaboration signed in July 2018 with Aston University in biofilms
  • Patent portfolio expanded with the grant of Canadian XF-biofilm patent
  • Most recent XF-73 microbiology testing confirms efficacy against 70 of the latest Staphylococcus aureus (SA) and methicillin-resistant Staphylococcus aureus (MRSA) strains
  • XF process chemistry, manufacturing scale-up and final formulation advanced to improve “cost of goods” and develop additional know-how

 

 

Corporate highlights

  • Experienced life science banker Nick Rodgers, appointed as a Non-Executive Director in June 2018, will assume the role of Chairman in December 2018, succeeding Sir Nigel Rudd
  • Jesús M González Moreno joins Destiny Pharma today as full time Chief Medical Officer
    • Dr González is an infectious disease expert with extensive experience and a proven track record in the clinical development of anti-infective drug candidates
  • Scientific Advisory Board established with leading experts in infection and hospital care to guide the strategy for the development of the XF platform
  • Collaboration with China Medical Systems progressing well with regular interactions on research, clinical development and regulatory strategy

 

Neil Clark, CEO of Destiny Pharma, commented:

“Destiny Pharma has made substantial progress in the year following its IPO in September 2017, delivering on a number of the clinical development and business objectives set out at the time.

 

“Our lead candidate, XF-73, remains firmly on plan to deliver important Phase 2b results in 2019 as part of a Phase 3 ready package. Importantly, a new market analysis report supports the clinical need and commercial opportunity for XF-73 in the prevention of post-surgical hospital infections, such as MRSA, which we estimate in the US to be a $1 billion sales opportunity.

 

“Following supportive Phase 1 data and an independent market analysis, we have announced today a new clinical programme for XF-73 as a potential $0.5 billion product for us in dermal infections. This programme will focus on addressing the significant unmet medical need and cost implications of infections associated with diabetic foot ulcers and burns wounds.

 

“Whilst our focus remains on our lead asset, we will also look to progress our new dermal clinical programme, with the Company well-funded through to H2 2020. With continuing international support for the development of novel anti-infective drugs that address the issue of anti-microbial resistance, Destiny Pharma’s unique platform is well-positioned to meet this global need and we remain confident in the outlook of the business.”

 

 

For further information, please contact:

Destiny Pharma plc

Neil Clark, CEO

Simon Sacerdoti, CFO

pressoffice@destinypharma.com

+44 (0)1273 704 440

 

FTI Consulting

Simon Conway / Victoria Foster Mitchell

destinypharma@fticonsulting.com

+44 (0) 20 3727 1000

 

Cantor Fitzgerald Europe (Nominated Adviser and Joint Broker)

Philip Davies / Will Goode, Corporate Finance

Andrew Keith, Healthcare Equity Sales

+44 (0)20 7894 7000

 

finnCap Ltd (Joint Broker)

Geoff Nash /Kate Bannatyne, Corporate Finance

Alice Lane, Corporate Broking

+44 (0)20 7220 0500

 

About Destiny Pharma

Destiny Pharma is an established, clinical stage, innovative biotechnology company focused on the development of novel medicines that represent a new approach to the treatment of infectious disease. These potential new medicines are being developed to address the need for new drugs for the prevention and treatment of life-threatening infections caused by antibiotic-resistant bacteria, often referred to as “superbugs”. Tackling anti-microbial resistance has become a global imperative recognised by the World Health Organisation (WHO) and the United Nations, as well as the G7 and the G20 countries. For further information, please visit https://www.destinypharma.com

 

Forward looking statements

Certain information contained in this announcement, including any information as to the Group’s strategy, plans or future financial or operating performance, constitutes “forward-looking statements”. These forward looking statements may be identified by the use of forward-looking terminology, including the terms “believes”, “estimates”, “anticipates”, “projects”, “expects”, “intends”, “aims”, “plans”, “predicts”, “may”, “will”, “seeks” “could” “targets” “assumes” “positioned” or “should” or, in each case, their negative or other variations or comparable terminology, or by discussions of strategy, plans, objectives, goals, future events or intentions. These forward-looking statements include all matters that are not historical facts. They appear in a number of places throughout this announcement and include statements regarding the intentions, beliefs or current expectations of the Directors concerning, among other things, the Group’s results of operations, financial condition, prospects, growth, strategies and the industries in which the Group operates. The directors of the company believe that the expectations reflected in these statements are reasonable, but may be affected by a number of variables which could cause actual results or trends to differ materially. Each forward-looking statement speaks only as of the date of the particular statement. By their nature, forward-looking statements involve risks and uncertainties because they relate to events and depend on circumstances that may or may not occur in the future or are beyond the Group’s control. Forward looking statements are not guarantees of future performance. Even if the Group’s actual results of operations, financial condition and the development of the industries in which the Group operates are consistent with the forward-looking statements contained in this document, those results or developments may not be indicative of results or developments in subsequent periods.

 

 

Chief Executive’s Statement

 

The global threat of anti-microbial resistance

 

Destiny Pharma is an established, clinical stage, innovative biotechnology company focused on the development of novel medicines that represent a new approach to the treatment of infectious disease. These potential new medicines are being developed to address the need for new drugs for the prevention and treatment of life-threatening infections caused by anti-microbial resistance (AMR).

 

AMR poses a threat to public health and is of serious concern to the World Health Organization (WHO) and other expert medical authorities. Lord O’Neill’s independent review on AMR, published in May 2016, predicts ten million deaths and an estimated $100 trillion cost by 2050. This major health issue continues to be highlighted, including in recent UK parliamentary committee discussions and within the US Food and Drug Administration (FDA) where the challenge of AMR is a priority. The FDA Commissioner, Scott Gottlieb, MD, commented, “As more and more bacteria grow resistant to currently available antibiotics, we must tackle the issue on all fronts and seek new approaches to this persistent and potentially deadly problem.”

 

Please see further information on the global issue of AMR from the FDA via the following link:

 

https://www.fda.gov/EmergencyPreparedness/Counterterrorism/MedicalCountermeasures/MCMIssues/ucm620149.htm

 

XF-73 nasal – significant commercial opportunity for highly-differentiated lead asset

 

The Company’s lead asset, XF-73, has been developed from Destiny Pharma’s novel, antimicrobial XF drug platform. Unlike most antibiotics, XF drugs have not been seen to generate bacterial resistance in industry-standard microbiology tests to date and therefore have significant potential to address the global threat of AMR. XF-73 has been shown to kill bacteria very rapidly and therefore may be an effective new treatment in the reduction of bacterial infections in hospital patients, including those caused by methicillin-resistant Staphylococcus aureus (MRSA). XF-73 is administered topically as a nasal gel whereby it reduces the nasal carriage of the bacteria Staphylococcus aureus (SA), which is the source of many post-surgical bacterial infections. Approximately a third of all patients globally have this nasal carriage as they enter surgery and, as a result, it is potentially a very valuable market due to the millions of surgical procedures carried out each year.

 

A new, independent study contracted by the Company interviewed anti-infections experts and payers in the US hospitals’ system and its conclusions in May have confirmed again the clinical need for the target product profile that XF-73 could deliver to reduce post-surgical infections. The report also supports the potential pricing and volume of eligible surgical procedures that contribute to a peak sales estimate of $1 billion in the US. The Company strongly believes that the prophylactic use of XF-73 and its unique AMR profile differentiates it from classical antibiotics whose use is limited by the threat of AMR.

 

XF-73 nasal – continued clinical progress

 

Destiny Pharma has continued to progress its clinical pipeline in 2018, finalising development plans for its lead asset, XF-73, for the prevention of post-surgical infections such as MRSA.

 

Destiny Pharma opened a US Investigational New Drug (IND) application for XF-73 in February 2018, which is a key regulatory prerequisite for conducting clinical trials in the country. This was followed by the FDA granting Fast Track designation for XF-73, for the prevention of post-surgical staphylococcal infections, in March 2018. The clinical programme for XF-73 has been further refined following discussions with the FDA and the Company is pleased that the regulatory body has clarified the requirements and timings of the additional Phase 1 safety studies, reducing the amount of Phase 1 data required ahead of the Phase 2b study.

 

The Company completed the first Phase 1 study, examining the potential of XF-73 to cause dermal irritation, in Q2 2018, with data readout in July 2018. The volunteer, blinded, placebo-controlled study demonstrated that XF-73 in solution, at high concentration, when applied daily for five days to intact and abraded skin has a similar irritancy potential to water (which was used as the control). This finding on abraded skin, combined with the lack of systemic absorption (no XF-73 was seen in blood samples taken throughout the study) supports the profile of XF-73 as a new treatment option for dermal infections. Following this supportive data and expert market analysis, the Company has finalised a new clinical programme to develop XF-73 as treatment for specific dermal infections as set out below.

 

The Phase 1 study results add to the existing strong safety and efficacy data set already established by Destiny Pharma in preparation for the Phase 2b study, planned to complete in H2 2019. The Phase 2b study is designed to assess the effectiveness of XF-73 nasal gel in significantly reducing nasal SA load prior to surgery, compared to placebo. The next Phase 1 study with XF-73 nasal gel is expected to complete in Q4 2018 in a similar skin irritation potential safety volunteer trial. On completion of this study, XF-73 nasal will be ready to commence the Phase 2b trial. The Company’s plan is to build a Phase 3 ready package consisting of the agreed clinical studies and concurrent toxicology and manufacturing projects.

 

In parallel with the clinical work, good progress has made with improving the efficiency of the synthesis pathway and scale up of XF-73 to improve further the costs of goods. Work is also progressing on possible final product presentations to enhance the ease of use in the hospital setting.

 

XF-73 dermal – new programme in multi-billion dollar dermal infection market

 

Destiny Pharma engaged expert consultants to review the multi-billion dollar dermal infection market and assess the clinical need, clinical development pathways, commercial opportunity and best fit for the XF drugs’ target product profile as a possible new dermal infection treatment. This work engaged with dermal infection experts in the US and Europe. Following an extensive review of dermal infection indications that XF-73 could potentially address, the Company will initially focus on developing XF-73 as a new treatment for diabetic foot ulcer infections (DFUs). Driven by the growing number of diabetics and associated complications such as infected DFUs, this represents a significant market opportunity for XF-73. As with all anti-infectives, AMR is also a concern within this market. There is no dominant treatment for DFUs and specialist physicians are therefore working to find better treatment options, including topical formulations. In addition, the target product profile of XF-73 tested favourably with dermal clinicians looking for better treatments for the smaller market for burns/wound infections.

 

Destiny Pharma is now progressing a new formulation of XF-73 for infections in DFUs and burns wounds, which is estimated to be a $0.5 billion global opportunity for the Company based on the incidence of such infections, the costs of the associated medical care and a realistic product pricing of XF-73 in this new market. In addition, XF drugs have the option of an extra mechanism-of-action through the use of photo dynamic therapy (PDT), which could be used to enhance potency and attack Gram-negative bacteria in these dermal indications.

 

The Phase 1 skin irritation study completed earlier in 2018 is the first data supporting the use of XF-73 on damaged skin. Following this positive data and the market analysis, the Company is now planning to undertake further work on formulation development, in in vivo models and Phase 1 studies (potentially in patients with the target infections) with the aim of being ready to start Phase 2 studies in 2020. Destiny Pharma has the funding to complete the work required to build this Phase 2 ready package, which is now the second clinical programme in the Company’s pipeline.

 

Research collaboration agreement and expansion of patent portfolio

 

Following the selection of the dermal infections as the second clinical programme, work on earlier programmes such as ventilator associated pneumonia (VAP), biofilms and other indications will be as research projects, including academic or commercial collaborations and grant funded programmes. In line with this strategy, Destiny Pharma signed a research collaboration agreement with an expert team at Aston University in July 2018 to examine novel compounds from the XF-platform and assess their potential to prevent, control and eradicate dangerous bacteria in biofilms. Serious infections are sometimes caused and exacerbated by biofilms where bacteria can hide and be protected from traditional anti-infective agents. XF compounds have already shown efficacy in biofilm models and this research project will explore the potential further, including looking at the mechanisms-of-action.

 

Destiny Pharma also continued to strengthen its patent estate, with the grant of the XF biofilm patent in Canada in February 2018, bringing the total number of XF platform granted patents to 95.

 

Board, SAB and management changes

 

In September 2018, it was announced that Sir Nigel Rudd would step down as Chairman in December 2018 after serving eight years as a Board member. Nick Rodgers, who was appointed Non-Executive Director in June 2018, will assume the role of Chairman following Sir Nigel’s departure. Nick was previously Chairman at Oxford Biomedica and has extensive experience of life science banking and advising listed companies.

 

In May 2018, the Company announced the formation of a Scientific Advisory Board (SAB) to provide expert, independent analysis of the Company’s research and clinical development plans and to help in developing clinical strategies for its unique XF platform. The SAB is made up of leading experts in the field of anti-infectives, who will provide clinical and scientific advice to the Company on current and potential new projects.

 

The Company is also pleased to announce today the appointment of Jesús M González Moreno, M.D. as full time Chief Medical Officer. Dr González is an infectious disease expert with more than 11 years’ experience of working within global pharmaceutical and biotechnology companies to design and execute clinical development plans for anti-infective drug candidates. He will play a key role in leading the clinical development of the Company’s pipeline.

 

Outlook

 

Destiny Pharma is well-funded to develop its lead asset, XF-73, through its clinical Phase 2b programme, which is expected to complete in H2 2019, delivering a robust package for partnering and/or further development into Phase 3, the final stage of clinical development. Importantly, recent US market analysis for this lead programme underlines the clinical need and $1 billion commercial opportunity for XF-73 in the prevention of post-surgery hospital infections, such as MRSA.

 

Destiny Pharma has also identified and initiated a new dermal infection clinical programme targeting a $0.5 billion peak sales opportunity where there is a significant unmet need for better anti-infective drugs treating diabetic foot ulcers and burns infections.

 

With continuing international support for the development of novel anti-infective drugs that address the issue of anti-microbial resistance, Destiny Pharma’s unique platform is very well-positioned to meet this global need and the Board remains confident in the outlook of the business. The Company is well funded to support activities through to H2 2020.

 

Neil Clark

Chief Executive Officer

26 September 2018

 

Condensed Statement of Comprehensive Income

For the 6 months ended 30 June 2018

 

  6 months ended

30 June 2018

Unaudited

£

6 months ended

30 June 2017

Unaudited

£

Year ended

31 December 2017

Audited

£

Continuing operations      
Revenue
Administrative expenses (2,122,464) (697,296) (2,511,871)
Other operating income
Share option charge (584,726) (305,234) (709,979)
Operating loss (2,707,190) (1,002,530) (3,221,850)
Finance income 124,123 59 10,459
Loss before tax (2,583,067) (1,002,471) (3,211,391)
Income Tax 306,458 82,427 233,908
Loss for the period (2,276,609) (920,044) (2,977,483)
Other comprehensive income
Total comprehensive loss from continuing operations
(2,276,609)
(920,044) (2,977,483)
 

 

     
Loss per share (Note 4)      
Basic and diluted (5.2)p (2.9)p (8.4)p

 

 

Condensed Statement of Financial Position

For the 6 months ended 30 June 2018

 

  As at

30 June 2018

Unaudited

£

As at

30 June 2017

Unaudited

£

As at

31 December 2017

Audited

£

ASSETS      
Non-current assets      
Property, plant and equipment (Note 5) 29,548 1,410 22,313
       
Current assets      
Trade and other receivables 634,020 150,183 277,126
Prepayments 38,055 59,641
Cash and cash equivalents 11,060,904 871,966 11,724,037
Other financial assets 4,000,000 5,000,000
Current assets 15,732,979 1,022,149 17,060,804
TOTAL ASSETS 15,762,527 1,023,559 17,083,117
       
EQUITY AND LIABILITIES      
Current liabilities      
Trade and other payables 768,768 93,953 397,475
Current liabilities 768,768 93,953 397,475
       
Shareholders’ equity      
Issued share capital 435,626 319,180 435,626
Share premium 17,292,284 17,292,284
Accumulated losses (2,734,151) 610,426 (1,042,268)
Total shareholders’ equity 14,993,759 929,606 16,685,642
TOTAL EQUITY AND LIABILITIES 15,762,527 1,023,559 17,083,117

 

 

Condensed Statement of Changes in Equity

For the 6 months ended 30 June 2018

 

 

 

  Issued share

capital

£

Share

premium

£

Accumulated
losses

£

 

Total

£

As at 1 January 2018 435,626 17,292,284 (1,042,268) 16,685,642
Total comprehensive loss (2,276,609) (2,276,609)
Share option charge 584,726 584,726
As at 30 June 2018 435,626 17,292,284 (2,734,151) 14,993,759

 

 

  Issued share

capital

£

Share

premium

£

Accumulated
losses

£

 

Total

£

As at 1 January 2017 638 18,335,074 (16,791,296) 1,544,416
Total comprehensive loss (920,044) (920,044)
Share option charge 305,234 305,234
Bonus issue of shares (Note 7) 318,542 (318,542)
Reduction of capital (Note 7) (18,016,532) 18,016,532
As at 30 June 2017 319,180 610,426 929,606

 

 

  Issued share

capital

£

Share

premium

£

Accumulated
losses

£

 

Total

£

As at 1 January 2017 638 18,335,074 (16,791,296) 1,544,416
Loss and total comprehensive loss for the period     (2,977,483) (2,977,483)
Share option charge 709,979 709,979
Bonus issue of shares (Note 7) 318,542 (318,542)
Reduction of capital (Note 7) (18,016,532) 18,016,532
Issue of share capital 116,446 18,165,573 18,282,019
Costs of share issue (873,289) (873,289)
As at 31 December 2017 435,626 17,292,284 (1,042,268) 16,685,642

 

 

Condensed Statement of Cash Flows

For the 6 months ended 30 June 2018

 

  6 months ended 30 June 2018

Unaudited

£

6 months ended
30 June 2017

Unaudited

£

Year ended

31 December 2017

Audited

£

Cash flows from operating activities      
Loss before income tax (2,583,067) (1,002,471) (3,211,391)
Depreciation charges (note 5) 3,850 750 2,077
Share option charge 584,726 305,234 709,979
Finance income (36,960) (59) (10,459)
(Increase)/decrease in trade and other receivables
(28,849)
66,337 (77,935)
Increase/(decrease) in trade and other payables
371,292
(60,805) 242,736
Taxation received 82,427 191,578
Net cash outflow from operating activities (1,689,008) (608,587) (2,153,415)
       
Cash flows from investing activities      
Purchase of tangible fixed assets (11,085) (999) (23,230)
Maturity of other financial assets 5,000,000
Purchase of other financial assets (4,000,000) (5,000,000)
Interest received 36,960 59 10,459
Net cash flow from investing activities 1,025,875 (940) (5,012,771)
       
Cash flows from financing activities      
New shares issued net of issue costs 17,408,730
Net cash inflow from financing activities 17,408,730
       
Net increase/(decrease) in cash and cash equivalents
(663,133)
(609,527) 10,242,544
Cash and cash equivalents at the beginning of the period
11,724,037
1,481,493 1,481,493
Cash and cash equivalents at the end of the period
11,060,904
871,966 11,724,037

 

Notes to the Condensed Financial Statements

 

  1. General Information

 

Destiny Pharma plc (“Destiny”, or the “Company”) was incorporated and domiciled in the UK on 4 March 1996 with registration number 03167025. Destiny’s registered office is located at Unit 36 Sussex Innovation Centre Science Park Square, Falmer, Brighton, BN1 9SB.

 

Destiny is engaged in the discovery, development and commercialisation of new antimicrobials that have unique properties to improve outcomes for patients and the delivery of medical care into the future.

 

 

  1. Basis of Preparation

 

As permitted by the AIM Rules, the Company Interim Financial Information for the period ended 30 June 2017 has not been prepared in accordance with IAS 34 “Interim Financial Reporting”. The results for the period ended 30 June 2017 are unaudited.

 

The Company Interim Financial Information has been prepared on a basis consistent with, and on the basis of, the accounting policies set out in the report and accounts for the year ended 31 December 2017. The Company Interim Financial Information has been prepared on the basis of the accounting policies, presentation, methods of computation and estimation techniques expected to be adopted in the financial information by the Company in preparing its next annual report.

 

A number of new standards and amendments to standards and interpretations have been issued but are not yet effective and in some cases have not yet been adopted by the European Union.

 

The Directors do not expect that the adoption of these standards will have a material impact on the financial information of the Company in future periods.

 

The interim accounts for the six months ended 30 June 2018 were approved by the Board on 25 September 2018.

 

The directors do not propose an interim dividend.

 

 

  1. Segmental Information

 

The chief operating decision-maker is considered to be the Board of Directors of Destiny. The chief operating decision-maker allocates resources and assesses performance of the business and other activities at the operating segment level.

 

The chief operating decision maker has determined that Destiny has one operating segment, the development and commercialisation of pharmaceutical formulations.

 

Geographical Segments

The Company’s only geographical segment during the period was the UK.

 

 

  1. Loss Per Share

 

The calculation for loss per ordinary share (basic and diluted) for the relevant period is based on the earnings after income tax attributable to equity shareholders for the period. As the company made losses during the period, there are no dilutive potential ordinary shares in issue, and therefore basic and diluted loss per share are identical. The calculation is as follows:

 

  6 months ended 30 June 2018

Unaudited

6 months ended 30 June 2017

Unaudited

 

Year ended

31 December 2017

Audited

 

Loss for the period from continuing operations (£) (2,276,609) (920,044) (2,977,483)
 

 

     
Weighted average number of shares 43,562,598 31,918,000 35,253,765
       
Loss per share – pence      
Basic and diluted (5.2)p (2.9)p (8.4)p

 

 

  1. Property, plant and equipment

 

  Plant and machinery
  £
Cost  
At 1 January 2018 79,376
Additions 11,085
At 30 June 2018 90,461
   
Depreciation  
At 1 January 2018 57,063
Charge for the year 3,850
At 30 June 2018 60,913
   
Net book value at 30 June 2018 29,548

 

 

  Plant and machinery
  £
Cost  
At 1 January 2017 56,147
Additions 999
At 30 June 2017 57,146
   
Depreciation  
At 1 January 2017 54,986
Charge for the year 750
At 30 June 2017 55,736
   
Net book value at 30 June 2017 1,410

 

 

 

  1. Property, plant and equipment (contd.)

 

 

  Plant and machinery
  £
Cost  
At 1 January 2017 56,147
Additions 23,229
At 31 December 2017 79,376
   
Depreciation  
At 1 January 2017 54,986
Charge for the year 2,077
At 31 December 2017 57,063
   
Net book value at 31 December 2017 22,313

 

 

  1. Share capital

 

On 24 January 2017, the Company undertook a bonus issue of shares whereby, in respect of each Ordinary Share in issue, 499 Ordinary Shares were issued, fully paid, resulting in a transfer of £318.542 from share premium to called up share capital.

 

On 26 January 2017, the Company effected a reduction of share capital whereby the outstanding balance on the share premium account, amounting to £18,016,532, was transferred to the profit and loss reserve.

 

 

  1. Events After the End of the Reporting Period

 

There are no events subsequent to the reporting period that require adjustment or disclosure.

 

  1. Copies of the Interim Financial Information

 

Copies of the interim accounts are available on the Company’s website at www.destinypharma.com and from the Company’s registered office, Unit 36 Sussex Innovation Centre Science Park Square, Falmer, Brighton, BN1 9SB.